Sildenafil is the ground breaking active ingredient in the original erectile dysfunction medication, Viagra. When Pfizer invented this pharmaceutical ingredient, they filed patents protecting its exclusivity which have recently expired. This means that pharmaceutical manufacturers can make their own generic equivalent of Viagra using Sildenafil Citrate as the main, active ingredient and sell it under a different trade name.
The medication was first developed as a medication to treat high blood pressure conditions, such as hypotension, as it is very effective as dilating blood vessels. Through clinical trials, researchers found out that it was even more effective at dilating the blood vessels in the soft muscle tissue of the penis. By doing this, the medication promoted unsuspecting erections in test subjects which led Pfizer to take it in another direction.
Sildenafil was approved by the FDA in 1998 for treating erectile dysfunction (sometimes called impotence) in male patients. Since it has been available as a generic medication, this product can now be purchased online, prescription free and at a much cheaper price than regularly charged at high street pharmacists. By purchasing this medication online, people can save time and money by avoiding the doctors and the chemists.
This product is approved by all major regulatory bodies including the FDA (US Food and Drug Administration), EMA (European Medicines Agency) and HC (Health Canada). Since the patent on Viagra expired, Sildenafil has become the most popular ingredient used in a wide variety of erectile dysfunction medications. As this substance has roots in treating hypotension, it can sometimes be prescribed off-label for this condition.
Erectile dysfunction is a condition that 20% of German males suffer with on a permanent basis. When a patient visits a doctor the first thing they will try to do is understand the cause of the condition, which can vary from physical ailments to psychological problems. This type of medication is usually used as a short term remedy for erectile dysfunction in those with treatable causes. Those with permanent erectile dysfunction from other conditions may use it more frequently.
Conditions like Diabetes can affect nerves which can cause erectile dysfunction. Other causes may be linked to how the body ages and the reduction of testosterone in elderly men. Sometimes, the cause can be depression, lack of confidence and porn addiction, which is usually the case with younger patients. Sildenafil is very effective and can alleviate the symptoms of erectile dysfunction regardless of the causes.
The way Sildenafil works is by preventing the production and release of an enzyme called PDE5 (phosphodiesterase 5), which is responsible for the breakdown of a cell messenger called cGMP (cyclic guanosine monophosphate). cGMP plays a big role in the internal mechanics of achieving and sustaining an erection as it signals the cells in the walls of blood vessels to dilate when sexually aroused.
When a man is sexually aroused, his body will respond in a number of ways. An erection is achieved by the body signalling the cells in blood vessels to dilate, heart rate increases and also breathing. cGMP is responsible for vasodilation, which means it makes blood vessels open more to allow more blood to flow through. When the blood vessels are relaxed, blood pressure increases to make the penis hard.
Once a man has ejaculated, his erection will subside, this is due to PDE5 consuming the cGMP resulting in the end of the blood vessels relaxing. Sildenafil prevents the release of PDE5, resulting in higher levels of cGMP which keeps the blood vessels relaxed and makes it easier to achieve and maintain an erection. These effects are enhanced when the user eats a well-balanced diet and maintains good hydration.
Whenever it is needed, Sildenafil can be taken orally. Although the effects of this medication may be felt sooner, doctors advise taking doses of this medication one hour prior to planned sexual activity. 1 x 100 mg pill per day, or every 24 hours, is the recommended dosage which should not be exceeded, in any circumstance. When this dosage is exceeded, users are more at risk of experiencing adverse effects.
When beginning treatments with Sildenafil, a lower dosage is recommended, especially for people who have never used it previously and for those 65 years of age and older. Due to the possibility that some patients may be sensitive to certain medications, doctors may opt to start new patients on smaller dosages. If a doctor determines it is required, this low dosage may be increased.
The FDA and Pfizer both participated in thorough clinical investigations before deciding on the recommended daily dosages of Sildenafil. The safest dosage that provides the advantages without any adverse effects is determined through clinical trials which last a long time. Only the benefits should be felt by the user, as long as the recommended amounts and frequencies are not exceeded.
The duration of action begins to take effect an hour after taking a dose of Sildenafil and lasts for a total of four to six hours. The effects of this drug could be delayed by a variety of conditions. People should refrain from eating heavy meals before dosages as this could hinder the drug from being absorbed. Meals high in fats, salt, and calcium can all slow down digestion.
Sildenafil may continue to be felt for up to 24 hours, even if its concentration peaks in the first four to six hours or an hour after taking it. As a result, patients should wait 24 hours between doses, even if a lower dosage is ineffective. The medication will have time to leave the body by doing this, making the subsequent dosage safe to take.
In spite of the fact that doses should never go over 100 mg in a 24-hour period, dosages may be raised if lower ones initially fail to produce the desired results. Many Sildenafil users claim that its advantages last longer than the suggested 6 hours. Because of this, guys who want to spend extended periods of time with their loved one commonly pick this product to improve their sexual performance.
Patients must be aware of any potential adverse effects before starting any new therapy. Most of the side effects of Sildenafil will disappear after it has had time to leave the body. The majority of this medications adverse effects are mild and manageable, but if any do arise or get worse, speak with your local physician for guidance on how to handle them.
The following are a few examples of the side effects of Sildenafil that occur most frequently:
Although they are the most frequent Sildenafil side effects, persons who take this medicine as prescribed should not encounter them.
Sildenafil side effects might include, but are not limited to:
Minimizing the risks of side effects should always be a topic people should research prior to beginning treatment. Taking Sildenafil properly as part of a treatment plan and not exceeding the maximum dosages are key to avoiding side effects. People should also make an effort to remain well hydrated when taking medication. For a full list, read the patient leaflet found on our website.
For most men, this medication is completely safe to use as it has been rigorously trialled and tested by the FDA with mild adverse effects only present in less than 1% of subjects. Sildenafil has been used widely since the release of Viagra, which shows how effective and safe it is. Even though this is a generic version, it still has to be made to the same high standards as the brand named counterpart.
The Office of Generic Drugs is a branch of the FDA which regulates generic medication manufacturers. The job of this department is to make sure generic copies are the exact same in regard to their strength, dosage form and quality. By doing this, they ensure that the generic versions of medications are just as safe as the original products by perfectly emulating them.
The improvement in blood flow that Sildenafil can give has also been shown to be beneficial for other things. Studies have shown the potential this substance has in slowing down dementia, it is also used by mountaineers to reduce the effects of altitude sickness. As improvements in circulation help deliver oxygen rich blood to the brain, more research in these areas is definitely needed.
Reviews play a massive part in our company development, without them we would not know which products are the most favoured. When looking at products like Sildenafil, at the bottom of the page, readers can add their own accounts of their experiences with that product. Not only do reviews help us but they are also very important to people who are new to a pharmaceutical product.
By providing your accounts and experiences using a medication, people can relate to it and decide if that product would be right for treating their condition or not. Reviews can also help people understand just how efficient the service was and if the stated delivery times are accurate. We highly encourage you to leave a testimonial yourself if you do decide to purchase Sildenafil.
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Buying medications with home delivery to Germany has never been easier, we have many sexual enhancement products available with Sildenafil being one of the most popular. When purchasing through our online pharmacy the benefits compared to high street pharmacies are important to note. As we offer high quality generics, the prices are much cheaper than those found in chemists in town.
That being said, quality is never compromised as these products are meticulously regulated by the Office of Generic Drugs. The price is only cheaper as generic manufacturers did not incur costs related to research, development, patenting or marketing, which are all very expensive. Due to avoiding these costs, medications like Sildenafil use the same formula but charge much less at retail.
Additionally, people can avoid the embarrassment of visiting a doctor and discussing their personal problems and then taking a prescription for erectile dysfunction medications to a chemist. Men can order Sildenafil directly to their homes without the need to even leave the house or have a consultation. This saves much time, effort and most importantly money.
We have the broadest range of sexual enhancement medications available on the market. Sildenafil is one of the most favoured medications on our list, however, we strongly recommend browsing through our product page to see more of what we have to offer. Ordering is easy, just add what you need to your cart, it is worth noting that we offer discounts on bulk orders and also discounts for paying by Bitcoin.
We accept Mastercard, Bitcoin and Visa and protect our website through 128-bit encryption, which is completely unbreachable. Payments will never show our company or our products on statements. Once payment has cleared, we will pick your order and pack it into unlabelled packaging, so no one will know what is inside. These are efforts we take to keep our service confidential when ordering products like Sildenafil.
Deliveries will be received in 4 - 7 working days for Germany and 5 - 7 days in the rest of Europe. If you have any questions related to our products or services, be sure to contact our customer services team through live chat or email.
Bring the spark back into your relationship with Sildenafil at https://kamagradeutschland.com.
Dr Hartman Welf is a renowned medical expert in the fields of urology and sexual health. He completed his undergraduate studies in Medicine at the University of Hamburg and later specialized in Urology and Sexual Health at the Ludwig Maximilian University of Munich.
Last Reviewed: 15th July 2024
Next Review Due: August 2025
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